Boswellic acids reduce Th17 differentiation via blockade of IL-1β-mediated IRAK1 signaling
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چکیده
منابع مشابه
IL-1β promotes Th17 differentiation by inducing alternative splicing of FOXP3
CD4(+)FOXP3(+) regulatory T (Treg) cells are essential for maintaining immunological self-tolerance. Treg cell development and function depend on the transcription factor FOXP3, which is present in several distinct isoforms due to alternative splicing. Despite the importance of FOXP3 in the proper maintenance of Treg cells, the regulation and functional consequences of FOXP3 isoform expression ...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 2014
ISSN: 0014-2980
DOI: 10.1002/eji.201343629